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SafeBridge Launches Predictive Tox Capabilities

Aims to enable higher throughput and risk prioritization strategies

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By: Kristin Brooks

Managing Editor, Contract Pharma

SafeBridge Consultants, a division of Trinity Consultants, Inc., has launched computational predictive toxicology services to the biopharmaceutical and chemical industry, designed to enable higher throughput and risk prioritization strategies.
 
SafeBridge is an authorized user of Derek Nexus from Lhasa Ltd., a knowledge-based expert system for the prediction of toxicological hazard, and Leadscope from Leadscope, Inc., a statistical predictive quantitative structure-activity relationships (QSAR) model.
 
SafeBridge will apply these two software packages to assist companies in meeting the proposed International Conference on Harmonization (ICH) M7 “Assessment and Control of DNA Reactive (Mutagenic) Impurities in Pharmaceuticals to Limit Potential Carcinogenic Risk” guideline; conduct risk assessments of extractable and leachable chemicals into drug products; assess the potential toxicity of contaminants in drugs; and assist in chemical synthetic process development.

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